Never take more than the prescribed dose. It works and leaves the body quickly, so it needs to be taken twice a day. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Many common herbal supplements interact with common heart medicines. Some of these medicine interactions can be risky. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. Accessed Sept. 7, 2022. It is also important information to carry with you in case of emergencies. Coenzyme Q-10 Natural Medicines. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. The herb licorice may lower warfarin levels and can add to digoxin's effects. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Please enable it to take advantage of the complete set of features! Hawthorn. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. Alcohol or marijuana (cannabis) can make you more dizzy. https://naturalmedicines.therapeuticresearch.com. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Isosorbide mononitrate helps to prevent angina chest pain from developing. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Some conditions may become worse when the drug is suddenly stopped. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. See the full pregnancy warnings document. This site needs JavaScript to work properly. https://naturalmedicines.therapeuticresearch.com. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Unable to load your collection due to an error, Unable to load your delegates due to an error. Seek alternatives to the CYP3A4 substrate when possible. Duplication for commercial use must be authorized by ASHP. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). This makes it easier for your heart to pump, relieving heart-related chest pain. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. This drug may make you dizzy. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Generic alternatives may be available. It has a very short duration of action and may not be suitable for some people. AskMayoExpert. This content does not have an English version. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. You may opt-out of email communications at any time by clicking on It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Nitroglycerin has an average rating of Enter other medications to view a detailed report. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. This should pass after a few days. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Using this medicine with any of the following medicines is not recommended. Do not take more or less of it or take it more often than prescribed by your doctor. Eur Heart J. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. It can make you really dizzy. Do not double the dose to catch up. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. It works by . Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Theyre fast, easy-to-use and free! Natural Medicines. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Although not all of these side effects may occur, if they do occur they may need medical attention. https://naturalmedicines.therapeuticresearch.com. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. It can cause your blood pressure to become dangerously low. Your dose may need to be gradually decreased. These headaches may be a sign that the medication is working as it should. Natural Medicines. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. This branded product is no longer on the market. The narrowing makes it more difficult for blood to flow to your heart muscle. Many people using this medication do not have serious side effects. Natural Medicines. In case of overdose, call the poison control helpline at 1-800-222-1222. Instead, the best way to dispose of your medication is through a medicine take-back program. Isosorbide mononitrate: isosorbide mononitrate. 55 ratings on Drugs.com. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. If you suffer headaches when taking Isosorbide mononitrate, be patient. You may report side effects to the FDA at 1-800-FDA-1088. However, you should not flush this medication down the toilet. Copyright, 2023. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Liperoti R, et al. National Library of Medicine Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Call your doctor for medical advice about side effects. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Does Alcohol Raise Your Blood Pressure? Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. I took this for 4 days, and my headaches were unbearable. Sept. 26, 2022. FOIA Accessed Sept. 7, 2022. Bookshelf Accessed Sept. 7, 2022. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Isosorbide mononitrate. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Take the missed dose as soon as you remember it. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. . St. John's wort. Mehta D. Botanical medicines. Methods: Please upgrade your browser or download modern browsers from here! Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Take care, thanks. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. For haemoglobin formation vit. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. In Canada - Call your doctor for medical advice about side effects. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). This survey is being conducted by the WebMD marketing sciences department. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Avoid combinations; the risk of the interaction outweighs the benefit. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Store it at room temperature and away from excess heat and moisture (not in the bathroom). prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. What happens if I stop taking isosorbide mononitrate (Monoket)? Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. 8.0 out of 10 from a total of Accessed Sept. 7, 2022. Take isosorbide exactly as directed. Available for Android and iOS devices. Treatment and prognosis of heart failure with preserved ejection . Highly clinically significant. Take your next dose at the regular time. Review/update the A single copy of these materials may be reprinted for noncommercial personal use only. If you notice other effects not listed above, contact your doctor or pharmacist. Never give it to other people even if their condition appears to be the same as yours. Consult your doctor for more details. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Take extra precautions to avoid falling during your treatment with isosorbide. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. The most common side-effect is headache. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. You can consult me online for homeopathic treatment. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Background: 8600 Rockville Pike Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Using this medicine with any of the following medicines is not recommended. Selected from data included with permission and copyrighted by First Databank, Inc. Real test is coronary angiography. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. Licorice. May also be prescribed off label for Esophageal Spasm. The .gov means its official. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Take the container with you, even if it is empty. Each day, take the first dose when you wake up, then take the second dose 7 hours later. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Integrative medicine (complementary and alternative medicine). It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. It is unknown if this medication passes into breast milk. Isosorbide mononitrate helps to prevent angina chest pain from developing. Do not stop taking it without consulting your doctor. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Use of herbal products and potential interactions in patients with cardiovascular diseases. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. These side effects may go away during treatment as your body adjusts to the medicine. Some don't work well with prescription medicines. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Thirty percent of the patients never experienced headache from the given dosages. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. HHS Vulnerability Disclosure, Help Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Changing positions slowly can help lessen dizziness. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Herbal supplements can strongly affect the body. Who should not take Isosorbide Mononitrate? Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. No, that's not true all the time. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Making any changes without doctor's advice can be dangerous. Yet many herbal supplements may interact with heart disease medicines. What side effects can this medication cause? Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. WebMD does not provide medical advice, diagnosis or treatment. Do infrared saunas have any health benefits? Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Do not change the dosing times unless directed by your doctor. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. A very serious allergic reaction to this drug is rare. These side effects may go away during treatment as your body adjusts to the medicine. We comply with the HONcode standard for trustworthy health information. You may report side effects to Health Canada at 1-866-234-2345. B12 and folic acid is essential along with iron. It is important that you follow the instructions your doctor gives to you about when to take your doses. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Egton Medical Information Systems Limited. If you have any questions about this medicine ask your pharmacist. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. My cardiologist recommended I get on metropolol. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Browse Drugs and Medicines. government site. Daily headaches are a common side effect. 1998 Oct;61(10):577-83. The site is secure. Follow directions about how much medicine to take. Click here for an email preview. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. This is so your doctor can check on your progress. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Keep all medications away from children and pets. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. Isosorbide controls chest pain but does not cure coronary artery disease. This site complies with the HONcode standard for trustworthy health information: verify here. Cardizem may also be used for purposes not listed in this medication guide. To provide you with the most relevant and helpful information, and understand which Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Talk to your provider if you notice your chest pain starts to get worse. If you have ever had an allergic reaction to a medicine. Natural Medicines. If you have any problems with the way your liver works, or any problems with the way your kidneys work. 2005 - 2023 WebMD LLC. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. This content does not have an English version. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Discuss the risks and benefits with your doctor. Alcohol can make the side effects from isosorbide worse. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. https://naturalmedicines.therapeuticresearch.com. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.