The gene is known as fibrillin-1 or FBN1. Congenital Heart Disease and Pediatric Cardiology, Invasive Cardiovascular Angiography and Intervention, Pulmonary Hypertension and Venous Thromboembolism, ACC Anywhere: The Cardiology Video Library, CardioSource Plus for Institutions and Practices, Annual Scientific Session and Related Events, ACC Quality Improvement for Institutions Program, National Cardiovascular Data Registry (NCDR), ACC.23/WCC Opening Showcase Presidential Address: Edward T. A. Fry, MD, FACC, Clinical Practice Algorithm For the Follow-Up of Repaired Coarctation of the Aorta, A 12-Gene Pharmacogenetic Panel to Prevent Adverse Drug Reactions, Post-Surgical Survival in Degenerative Mitral Regurgitation, Phenotypes of Overdiagnosed Long QT Syndrome, Congenital Heart Disease and Pediatric Cardiology, Invasive Cardiovascular Angiography and Intervention, Pulmonary Hypertension and Venous Thromboembolism, Dilated aorta (z-score >2) AND ectopia lentis = Marfan syndrome*, Dilated aorta (z-score >2) AND systemic score >7 (see Table 2 below) = Marfan syndrome*, Ectopia lentis AND family history of Marfan syndrome = Marfan syndrome, Systemic score >7 AND family history of Marfan syndrome = Marfan syndrome*, Dilated aorta (z-score >2 above 20 years old; z-score >3 below 20 years old) AND family history of Marfan syndrome = Marfan syndrome*. There was evidence of weight loss and muscle wasting in several photographs of Lincoln, which could indicate that he had Marfan Syndrome. Ocular findings in 87 adults with Ghent-1 verified Marfan syndrome. People with Marfan syndrome often have tall, slender bodies and long limbs. Isaiah Austin, a star basketball player from Baylor University, was diagnosed with Marfan syndrome in the weeks prior to the 2014 NBA draft (Figure 1). His violin technique demanded a wide use of harmonics and pizzicato effects, and new techniques of fingering. His looks were partly the result of the MS. Healthsoothe does not provide medical advice, diagnosis, or treatment. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Famous People With Borderline Personality Disorder, https://www.nichd.nih.gov/health/topics/klinefelter/clinicaltrials/default, 11 Essential Oils For Bipolar Disorder (Manic-Depressive Illness), Benefits of Using Herbal Teas for Natural Healing (And Pain Relief). Robert Johnson was an American blues singer and musician who is considered one of the most influential blues musicians of all time. His premature death, at the tender age of 19, ignited historians speculations of Marfan. Despite his unusual appearance, Lincoln was a gifted politician and talented leader. The diagnosis of Marfan syndrome is based on the Revised Ghent Criteria, which encompasses family history, physical features, imaging (echocardiogram), ocular evaluation (slit lamp eye exam), and genetic testing (Table 1).1 Examples of the physical characteristics of Marfan syndrome, differential diagnosis, calculation of the systemic score (Table 2), z-score determination and aortic size nomograms are available at the Marfan Foundation website and in the Marfan Foundation's mobile app, Marfan Dx (which can be downloaded from the website for use on a smart phone or tablet). Modified from Loeys BL, Dietz HC, Braverman AC, et al. Studies show that most Marfan syndrome cases are inherited. As a tween, Flo developed rapid bone and tissue growth in various parts of her body, which made her self-conscious. We invite you to contact us regarding any inaccuracies, information that is out of date or any otherwise questionable content that you find on our sites via our feedback form. When suspicion of Marfan syndrome is raised, an echocardiogram and a slit lamp eye exam are necessary. Sadly, he died on 12th November, 2013, at his resident in Dorset. For this purpose, he has used the name Atlas Sound. His rock band Deerhunter is a very famous musical band. Julius Caesar was one of the most famous and influential political leaders in history. His death is a major issue of medical malpractice. MS is caused by a defect, or mutation, in the gene which determines the structure of fibrillin-1, a protein that is an essential part of the connective tissue. Best Mouthguards for Teeth Grinding and Snoring! . He is an American musician and singer-songwriter, best known as the lead singer and guitarist of the indie rock band Deerhunter. If you or someone you know has Marfan syndrome, remember that you are not alone and there are resources available to help you manage the condition. He has been diagnosed with a mild form of Marfan syndrome, a condition that affects the connective tissue in the body. When the dura expands, it puts pressure on the lower back leading to: More than five in ten[5] individuals with the syndrome experience eyesight issues, including short-sightedness, lens subluxations, or have partial lens dislocation in one or both eyes. Even if it might sound like a condition off the surface of Narnia, studies show Marfan syndrome is more common than you would think. Jonathan Larson was an American composer and playwright, best known for creating the Broadway musical Rent. It affects both men and women of all ethnic groups. How did Marfan syndrome consume this talented personality? He died of lung cancer at age 57 in Italy. We are independently owned and the opinions expressed here are our own. Marfan syndrome is a genetic disorder that affects the connective tissues in the body. On June 22, 2014, Isaiah had been diagnosed with Marfan syndrome. The album is that part of his life that he has lived because of Marfan syndrome. There are many famous Marfan syndrome sufferers. All his compositions are incredible, and he was awarded many times for his outstanding work. Management commonly includes the use of beta-blockers, like ACE inhibitors or propranolol. He is an American professional basketball player who played 2 years of college basketball at Baylor University. Peter earned a place in cinematic history for his role as Chewbacca in the Star Wars franchise. With a total of 22 medals, he's rightly called the most decorated Olympian of all time. The main blood vessel aorta grows and grows and reaches a point where it bursts. John Tavener had two heart attacks because of this disorder. The Italian actor was even a member of the National Marfan Foundation, which helped individuals cope with the condition, as well as spread awareness regarding the disorder. Marfan syndrome can cause problems in many different parts of the body, including the skeleton, People with Marfan syndrome often have tall, slender bodies and long limbs. 4. He was also diagnosed with Marfan syndrome. Niccolo Paganini 6. If you think that's all in the list of famous people havingMarfan syndrome, you'll be up for a surprise because there are many other big names as well. People with Marfan syndrome are usually tall and thin with unusually long arms, legs, fingers and toes. His film debut came in 1971 with "The Panic in Needle Park". His bony and long face with long arms and fingers is certainly pointing to the fact that he suffered from this disorder. It was here that he first began to compose music. Schiavelli learned about the Marfan syndrome at the age of 9 years, when his eye specialist detected dislocated lens. Athletes with Marfan syndrome are not recommended to participate in activities that involve sustained muscle contraction such as weight lifting or rock climbing. Marfan syndrome affects the body's connective tissue and can cause problems in the eyes, joints, and heart. This causes the tearing of the aorta wall. The life expectancy of people with Marfan syndrome has improved since 1970. He was diagnosed with Marfan syndrome in 1990 and lived with this for about 23 years. His compositions include the Piano Concerto No. Lens dislocation occurs in approximately 60% of people with Marfan syndrome.2 The majority of Marfan patients have mitral valve prolapse. The prevalence of the syndrome is 7-17/100,000. Nicknamed Flo, the outstanding athlete, was an Olympic silver medalist and renowned volleyball player for the US. While there is no cure for Marfan syndrome. He was a famous violinist. Originally named Bradley, she was assigned the male gender at birth and went to an all-boys school. Osama Bin Laden Born in the family of sixteen children, Bin Laden was 6' 6" tall. 7 Niccolo Paganini. J Med Genet 2010;47:476-85. New guidelines for disqualification from competition for athletes with aortic disease including Marfan syndrome have been sanctioned by the American Heart Association and will be published soon. His hands (most likely due to this syndrome) were the largest he had ever seen, with a stretch so wide that they covered the keyboard like octopus tentacles.. Marfan syndrome that affects your connective tissue is a genetic disorder. Diagnosis of Marfan syndrome is very important as it affects many body tissues or, more clearly, almost all the bodys cells and tissues. Sitwell was also a noted critic, and wrote several books on art and literature. Accordingly, we want you as a visitor to understand the instances where we get paid to promote and sell products on this site. The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm. Over the years, he has won many accolades recognizing his dedication and hard work to swimming, including a few Espys and Sportsman of the Year in Sports Illustrated. However, her mother encouraged her to use these adversities to her advantage. 556. Another individual with the Michael Phelps Marfan syndrome symptoms is John Taverner. Julius Caesar is an example of someone with Marfan syndrome who achieved great things despite the challenges posed by his health condition. He never let his disorder come in his way and showed great courage to restore the old traditions of Egypt and moved his capital back to Memphis. The cause of her death was fatal aortic dissection due to Marfan syndrome. He is a South African-born Australian songwriter, singer, actor, and YouTube personality who has a mild MS. On the 24th of January 1986, Flo Hyman died at the young age of 31 after collapsing during a game in Japan. There is no cure for Marfan syndrome, but treatments can help to manage the symptoms and reduce the risk of complications. (Detailed Guide), Ideal Body Proportions Calculator For Athlete. Their arms, fingers, legs, and toes might seem out of proportion, too long and slender for the rest of their body. His extraordinarily long fingers had an association with the console in a way that captivated his audience. Aorta stretch to a level that causes the aortic valve to leak. Arik had MarfanSyndrome. Here is a list of famous people with Marfan syndrome. People with Marfan syndrome are at increased risk of developing cardiovascular problems, such as aortic aneurysms and mitral valve prolapse. Marfan syndrome is an inherited disorder that affects connective tissue the fibers that support and anchor your organs and other structures in your body. In addition to his acting career, Schiavelli was also a writer and director. Cox has said that he is "lucky" to have the Marfan syndrome because it has helped him to be creative and to stand out from other people. Wear bulky clothes and be a shoegazer and stare at my feet and act all sensitive? READ THIS NEXT: Salami vs Pepperoni Differences, Lux interior died of aortic dissection age 62 lead singer founder of The Cramps, Lock Martin had MS. Michael Phelps is a famous swimmer Olympian. The treatment consists of one-to-two dozen shots every seven days. When evaluating the athlete with aortic dilatation and suspected Marfan syndrome or related disorder making the correct diagnosis is imperative. In 1936, Johnson recorded his first and only studio album, titled "Robert Johnson: King of the Delta Blues Singers." Abraham Lincoln Lincolns mercury poisoning Did you ever hear of Lincoln's sign? In 1962, according to Lincolns photograph, Harold Schwartz said he might have aortic insufficiency. In an interview, Peter said: I dont have the big head, but of a connective tissue disorder called Marfan syndrome., The most significant risk is that people can have a problem with their heart., READ MORE: Rice Vinegar vs Rice Wine Vinegar. Build A Successful Homecare Business With These Tips. During an interview, he said: So I was all my life very flexible, all my life doing weird tricks and things to enjoy with my friends [using] very creepy movement., I have a disease called Marfan syndrome. The following 21 pages are in this category, out of 21 total. READ MORE: Interesting Facts About Leukemia. He was a tall, lanky man with a prominent mole on his chin. Stretch marks are not related to weight changes, especially on the hips, lower back, and shoulders. #marfan, #syndrome, #famouspeoplewithmarfansyndrome, #celebrities, #celebritieswithmarfansyndrome. This Knowledge enabled Schiavelli to get proper preventive measures. CHRIS PATTON, Patton, a teammate of Brown's at Maryland, died of a ruptured aorta, the main blood vessel leading from the heart, during a pickup basketball game in April 1976. Top 10 Famous People with Marfan SyndromeSyndromes in addition to disorders have for all time been an interesting ingredient of the biological world. At no time do we advise any of our readers to use any of our content as a substitute for a one-on-one consultation with a doctor or healthcare professional. Marfan syndrome is an inherited disease that affects the bodys connective tissue, which provides support, strength, and elasticity to blood vessels, cartilage, heart valves, tendons, and other important parts of the physical body. Rachmaninov was also tall and slender with a small head and long nose, which was an indication of the famous Marfan syndrome. Individuals with Marfan syndrome might have a dental history of tooth extractions. Despite his short life, Robert Johnson left a lasting legacy through his music. What are some famous people with Marfan syndrome? Treatment of Marfan syndrome extraordinarily improves life expectancy. Does anyone know if actor John Smith had MS? He had two successive heart attacks, which made him very weak. Photograph courtesy of Baylor University, with permission. Sivan has spoken openly about his diagnosis and how it has affected his life. If someone has been diagnosed with Marfan syndrome, they should go for routine checkups and consult cardiologists. Mary also didn't die because of Marfan syndrome instead she was sentenced to death because of treason. Contributing your product facts helps to better serve our readers and the accuracy of the content. Julius Caesar was a roman statesman, a general and a distinguished author of Latin prose. Spontaneous pneumothorax due to apical pleural blebs occurs in 5% of people with Marfan syndrome. He is the pillar of modern violin technique. He died at the age of 74 at Ichilov Hospital in Tel Aviv, a few hours after he suffered a fatal hemorrhage. Earlier life expectancy was 32 years, but if diagnosed at a young age and controlled for risk factors, the progression of the disease can be stopped. READ MORE: Celebrities With Turner Syndrome. Jonathan Larson was also a famous music composer, but his fame came only after his death. Tavener was diagnosed with MS in 1990, aged 46. Given Lincolns unusually tall height and unusual physical gifts, Dr. Abraham Gordon proposed in 1962 that he had Marfan syndrome. By reading this article, you can get inspirational messages from the life of these famous people with Marfan syndrome. He died when he was 19 years old. First Bank Routing Number 2022 See How to Find Your Routing Number. Keywords: Aorta, Aortic Aneurysm, Aortic Aneurysm, Thoracic, Arachnodactyly, Athletes, Basketball, Body Size, Chromosomes, Human, Pair 15, Craniosynostoses, Diagnosis, Differential, Dilatation, Dilatation, Pathologic, Ectopia Lentis, Ehlers-Danlos Syndrome, Enophthalmos, Funnel Chest, Genetic Testing, Genetics, Medical, Hypertelorism, Kyphosis, Loeys-Dietz Syndrome, Marfan Syndrome, Microfilament Proteins, Mitral Valve Prolapse, Mutation, Myopia, Nomograms, Phenotype, Physical Exertion, Pneumothorax, Retinal Detachment, Retrognathia, Sclera, Scoliosis, Sports, Syndrome, Uvula, Viverridae, Transforming Growth Factor beta3, Universities. Pound encouraged her to experiment with her style and form, and she went on to become one of the most original and innovative poets of her generation. Noteworthy, Isaiah Austin had suffered a retinal detachment at age 11, which was ascribed to trauma related to a baseball injury. Caesar was assassinated in 44 BCE by a group of conspirators who were afraid of his power. He died in 1840 due to internal hemorrhaging. Our website uses cookies to improve your experience. They often progress or become worse with age. As a final example of suspected Marfan syndrome in famous people, we should mention a rather lengthy superstar. For an optimized experience on mobile, add Top 13 Famous People With Marfan Syndrome You Didnt Know About shortcut to your mobile device's home screen, 2023 Healthsoothe. Shiavelli said that Paganinis pattern of violin technique was so challenging and difficult that, to date, no one could play it like him. Gillis E, Van Laer L, Loeys BL. Marfan syndrome affects the heart, blood vessels, eyes and skeleton. He was the founder of al-Qaeda and was hunted down to put an end to an era of terrorism and suffering. Tall and thin, long fingers and feet, crooked spine. The Marfan syndrome is an autosomal dominant disorder of the connective tissue with mutations on the fibrillin-1 gene encoding for fibrillin, a major component of the extracellular microfibrils. We read how Marfan syndrome can be complicated, but the main focus is on the message this article wants to give to all the people reading this. However, among the list of people with Michael Phelps Marfan syndrome, Vincent was among the first. People with Marfan syndrome describe the symptoms in very different ways. According to some sources, the Olympic swimmer and gold medalist has this syndrome, but some are contesting this since swimming at a high level with MS would be hard. Introduction
Today Cox is 40 years old and living his life in his own way. The connective tissue disorder, which is sometimes referred to as the. treatments can help to manage the symptoms and reduce the risk, health issues he suffered from throughout his life is also an indication of the existence of the genetic disorder, treatments are available to help manage the symptoms and prevent complications, Different Weed Products That Are A Must Try This Fall, Why Investing in a Healthy Lifestyle Is Always Worth It, Philtrum | Everything you Need to Know About It (with pictures, videos, and FAQs), What Are The Benefits Of Combining Wellbutrin And Zoloft? How did this happen? Now let me tell you a unique story of Niccolo Pagnini. They just gave me the idea that I am a younger athlete and should get my electrocardiogram done to get the status of my heart health. 17 Famous People With Klinefelter Syndrome or Marfan Syndrome 1 Austin Carlile. https://www.nhlbi.nih.gov/health-topics/marfan-syndrome, https://hub.jhu.edu/2013/12/05/hal-dietz-marfan-syndrome/. Everything You Need To Know, Ultimate Guide to Getting Clear Skin in No Time, The Most Famous People Dealing With Marfan Syndrome, https://www.ncbi.nlm.nih.gov/books/NBK537339/, https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.031264, https://pubmed.ncbi.nlm.nih.gov/12177551/, https://rarediseases.org/rare-diseases/marfan-syndrome/, Learn About the Symptoms and Treatment of Sjgrens Syndrome. In addition, he worked at the national conference helping teens with MS, whom he called his genetic brothers and sisters.. An aim of teaching health to the people. Speak to those who have the same disorder and experienced Marfan disorder. Some of the, A Professional Advice on "Watery Discharge Feels Like I Peed Myself", 10 Hair Loss Remedies - Conquering Hair Loss In Natural Way. Other famous Marfan syndrome symptoms include: Most individuals with Marfan syndrome eventually need preventative surgery to repair heart issues. While there is no cure for Marfan syndrome, treatments are available to help manage the symptoms and prevent complications. It makes people skinnier, taller, and very flexible.. The famous actor, singer, songwriter, and guitarist was a member of the rock band Deerhunter. Take away points from the life of famous people with Marfan syndrome, Your email address will not be published. Life can depend upon it. The revised Ghent nosology for the Marfan syndrome. The famous people with Marfan syndrome have suffered from genetic disorder of connective tissues in their body. In bin Laden's case, it is believed that his Marfan syndrome contributed to his death in 2011 when he was shot by US forces during a raid on his compound in Pakistan. Other people develop dural ectasia[4], the enlargement and weakening of the dura, a membrane that surrounds the brain and spinal cord. He is the guitarist and lead singer of the Indie rock band, Deerhunter. Top 10 Famous People with Marfan Syndrome. The victims of this disease suffer defects of heart valves. This paper will aim to review cardiovascular pathophysiology and assessment in relation to Marfan syndrome with particular reference to echocardiography and the athletic population. Robert johnson 3. The condition is caused by a mutation in the FBN1 gene, which controls the production of fibrillin-1, a protein that is essential for the formation of connective tissue. He was born in 1782 with the Marfan syndrome, and his symptoms included long limbs, scoliosis, and thinning of the skin. His height is not a product of gigantism. His normal visual acuity and unremarkable cardiovascular history raised objections to this hypothesis. Patients with Marfan syndrome are at risk for retinal detachment, and ectopia lentis (lens dislocation) is a hallmark feature. He also composed several works for the violin, which are still performed today. All rights reserved. He was a country musician in the Los Angeles area. He was the 11th pharaoh of the Egypt's 18th dynasty and should not be missed among the list of most famous people with Marfan syndrome. He was born in Rome in 100 BCE and rose to power through his military campaigns and political alliances. The condition was rooted in his family, as most of his cousins were struggling with the disorder. Michael Phelps. His first big screen movie was Dallas buyers club, one of the most widely acclaimed movies. His parents encouraged him to pursue his musical interests, and he was also influenced by his father, who was an organist for a Presbyterian church. Phelps won 6 gold medals at the 2004 Olympics, 8 gold medals at the 2008 Olympics, and 4 gold medals at the 2012 Olympics. He was diagnosed after spending 46 years struggling with it. Jonathan David Larson was one of the most famous people with Marfan syndrome. Larson died of a tear in his aorta, believed to have been caused by MS. Participation in competitive athletics for the individual with Marfan syndrome is prohibited except for low intensity sports such as golf, bowling, and others not associated with intense physical exertion and bodily collision as outlined in the 36th Bethesda Conference5 This recommendation is based on the concern that more intense sports with higher levels of isometric and dynamic exercise leads to greater aortic wall stress and increases the risk for aortic dilatation and dissection. She was on the United States Olympic squad in 1980 and 1984. He is still one of the most revered personalities in the history of the world, and is definitely among the most famous people with Marfan syndrome. He was a Chicago Public Schools principal whose energy,resourcefulness and leadership inspired his students and helped engineer a school merger that suffered from MS and died in hospice care on March 5, 2018. She is best known for her eccentric and unconventional style. that appear throughout our content. Please let us know in the comments below. Add Top 13 Famous People With Marfan Syndrome You Didnt Know About to Home Screen, 1) Press the share button on your browser's menu bar, 13 Famous People With The Marfan Syndrome. John Tavener. I am constantly striving to learn new things and to be the best at what I do. His joints were so flexible that he played the violin in a very unique way. So did Julius Caesar and Tutankhamen. However, it is not always a result of genetic issues. Troye Sivan is a prominent Australian singer, songwriter, actor, and a YouTuber born on the 5th of June, 1995. Other notable people assumed to have had it include blues singer-songwriter Robert Johnson, Russian pianist Sergei Rachmaninoff, and Italian violinist Niccolo Paganini. In Marfan syndrome approximately 25% of cases are due to a spontaneous mutation, and neither parent has the condition. Letters have been sent to Mary stating the plot of assassination, but later on royal guards intercept the assassination. The severity of this syndrome varies from one individual to another, and it usually progresses over time. I think its more common than reported, because so many, go undiagnosed. 14 Essential Things to Know, Patients with Marfan syndrome and long and flexible fingers. In 2005, Austin formed Call It Even with his high school friends. Bradford Cox Those emotional first lyrics of Cox 8. From athletes to actors to musicians, these individuals have all achieved great things despite their condition. He was diagnosed with the condition in 1990 and has had two . He studied music at Highgate School. She began her professional career with the New York Stars of the now-defunct United Volleyball Association (UVA). He died at the young age of 27 years. He was physically and psychologically affected when he took mercury and opium as remedies. However, the diagnosis was uncertain as he was not considered to have many of the outward features. Are you looking for a way to calculate how many calories youve burned during your, Get the latest creative news from Healthsoothe about health and dentalcare. Tut has a curved spine and unusually tall and slender stature, and his parents believed him to possess similar traits. Devereux RB, de Simone G, Arnett DK, et al. They also typically have exceptionally flexible joints and abnormally curved spines. Evaluation in a specialized center with cardiology and medical genetics expertise in Marfan syndrome and related disorders is recommended when the diagnosis is uncertain or for confirmation of diagnosis and treatment when appropriate. Some even say his long fingers were made him one of the best music composers of the 19th-20th Century. All Health Web Magazine content is thoroughly reviewed and/or fact-checked by a team of health industry experts to ensure accuracy. Phelps was never a fan of swimming and was so afraid of it that he'd only floated around on the back of his instructor. He died in 2013 at the age of 69. If modern genetic tests had been available at that time, it might have been possible to find out whether it was Ehler-Danlos syndrome or Marfan syndrome exactly. Vincent Schiavelli was an American actor best known for his work in films like "One Flew Over the Cuckoo's Nest" and "Ghost". People with Marfan syndrome correctly diagnosed and treated (before aortic dissection) have an average lifespan which approaches that of the general population.7 Routine, safe levels of aerobic activity are important for health and well-being, including for those with Marfan syndrome. Update Phelps wrote in his book that he was checked for MS at Johns Hopkins University and the results were negative. Abraham Lincoln Abraham Lincoln, the 16th president of the United States, was born on February 12, 1809, in Hodgenville, Kentucky. The condition becomes life-threatening if it affects your blood vessels or heart. Michael Phelps is definitely a name to remember when you talk about famous people havingMarfan syndrome who made great name in music, but Sergei Rachmaninov is another big name with Marfan syndrome who was a great conductor, composer and pianist. He has also said that he is careful not to overdo it physically because of the risks associated with the condition. The album was a critical and commercial success, and it cemented Johnson's place as one of the most important blues musicians of all time. People with Marfan syndrome are living a healthy life just because they were timely diagnosed and treated. Austin is undergoing a long procedure to battle the effects of Marfan syndrome. He had to drop out of high school when he was a teenager, and his childhood was mostly lonely due to his parents divorce. He was a patient of Marfan Syndrome and died on May 27, 1840. Cherylee Houston has been battling with Ehlers-Dalos syndrome since the age of 23. Over the years, he has won many accolades recognizing his dedication and hard work to swimming, including a few Espys and Sportsman of the Year in Sports Illustrated. He got his heart surgery done. Bradford Cox The lyrics of this album were mixed with a lot of criticism, but many people traced his emotions. At the age of 10 to 12, Bradford started to notice symptoms of famous Marfan syndrome. He had one bad eye and unnatural long fingers. People who have KS have an increased risk for autoimmune disorders, like rheumatoid arthritis, lupus, and Sjogrens syndrome. People with Marfan syndrome usually live normal life spans, but they are at increased risk for developing serious health complications such as heart disease or an aortic aneurysm (a ballooning of the major blood vessel that carries blood from the heart to the rest of the body). Maron BJ, Ackerman MJ, Nishimura RA, Pyeritz RE, Towbin JA, Udelson JE. Marfan's syndrome results from a gene mutation that leads the body to overproduce a particular proteincalled transforming growth factor beta (TGF-) causing problems in connective tissue that. Here Is A List Of 18 Famous People With Marfan Syndrome: #1 Michael Phelps Getty Images He is an American former competitive swimmer and the most decorated Olympian of all time.