1-800-FDA-1088. They can recommend ways to maintain a healthy weight. If you drink alcohol, talk with your doctor about how much may be safe to consume while youre taking Eliquis. What should I do if I become pregnant during Eliquis treatment? These are not all of the possible side effects of ELIQUIS. Please see U.S. Full Prescribing Information, including Boxed WARNINGS and MedicationGuide. Does Eliquis interact with other drugs you are taking? Ask them what other medications are better options for you. They can become very itchy. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. This clot may press on your spinal cord, which could cause long lasting or even permanent paralysis. You should also call your doctor right away if you fall and hit your head or have any other kind of head injury. Learn more below. Upcoming surgical or dental procedures. If you have to stop taking ELIQUIS, your doctor may prescribe another medicine to help prevent a blood clot from forming. Eliquis (apixaban) tablets, for oral use (2021). Get medical help right away if you have sudden chest pain or chest tightness, have sudden swelling of your face or tongue, have trouble breathing, wheezing, or feeling dizzy or faint. For People at Risk of Stroke due to AFib Not Caused by a Heart Valve Problem. Liver problems. Store at room temperature away from light and moisture. Theyll discuss whether Eliquis may be a safe treatment option for you. Learn more about some of the side effects Eliquis may cause. However, older adults may be more likely to have conditions that can raise the risk of side effects with Eliquis. If you cannot swallow the tablet whole, you may crush the tablet and mix with water, apple juice, or applesauce and take it right away. Learn more here. ELIQUIS (apixaban) is a prescription medicine used to reduce the risk of stroke and blood clots in people who have atrial fibrillation, a type of irregular heartbeat, not caused by a heart valve problem. Itching is common in many drug rashes. These are considered drug-condition or drug-factor interactions. It doesnt affect the way the medication works. If you have constipation or diarrhea with Eliquis, talk with your doctor. First a patch on my foot that appeared to be ringworm and did actually respond to ringworm creams, but did not clear up and is still here. If you develop serious side effects while taking Eliquis, call your doctor right away. If you have to stop taking ELIQUIS, your doctor may prescribe another medicine to help prevent a blood clot from forming. This type of rash looks red, often starting on the face and upper body. Call your doctor or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS: Spinal or epidural blood clots (hematoma). However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Cellulitis may also occur on the arm, breast, abdomen, and other areas. You shouldnt stop taking Eliquis suddenly without talking with your doctor. Consult your doctor before breast-feeding. ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. However, these side effects werent reported in clinical trials of Eliquis. Theproducts discussed herein may have different product labeling in different countries. The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. Stopping ELIQUIS increases your risk of having a stroke. People who take ELIQUIS, and have medicine injected into their spinal or epidural area, or have a spinal puncture, have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). If you stop taking Eliquis earlier than your doctor recommends, this increases your risk of developing blood clots. LCV is a histopathologic diagnosis given to a small-vessel vasculitis where immune complexes deposit in the vessel walls. Multi ingredient medications may also be listed when applicable. These include severe urticaria, erythroderma, SJS/TEN, anticoagulant-induced skin necrosis, and DRESS. Other drugs that have the same active ingredients (e.g. If you have any active bleeding, your doctor will not recommend that you start taking Eliquis. This is to reduce your risk of bleeding. The study is based on apixaban (the active ingredients of Eliquis). The products discussed herein may have different product labeling in different countries. They may be able to recommend ways to treat this side effect. There are many possible triggers of these digestive problems. Eliquis hasnt been studied in people with an artificial heart valve. This medication can cause bleeding. This can help them determine if the drug is a safe treatment option for you. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. During your Eliquis treatment, consider taking notes on any side effects youre having. This offer is non-transferable, no substitutions are permissible, and offer cannot be combined with any other rebate/coupon, free trial, or similar, Bristol-Myers Squibb and Pfizer reserve the right to rescind, revoke, or amend. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). There are many things people can eat and drink that may help keep the blood thin and reduce the chances of developing dangerous clots. If you have a spinal procedure while taking Eliquis, you may have a higher risk of spinal blood clots if you: Symptoms of a spinal blood clot may include: If you need to have a spinal procedure while taking Eliquis, make sure your doctor knows that youre taking this medication. Talk with your doctor about how long you should take Eliquis. You should not do both. You may notice small, raised or flat lesions on reddened skin. Feeling of warmth on the skin. Tell your doctor about all of the medicines you take, Ken shares about talking with his doctor after being diagnosed, Watch Dr. Nayak explain the importance of coming to your doctor with questions, Myra shares how she learned about her diagnosis, Joe describes being diagnosed and choosing ELIQUIS with his doctor, How AFib not caused by a heart valve problem can lead to a stroke. If you have a cut while taking Eliquis, press on it with a clean cloth or dressing for 10 minutes to help stop the bleeding. In the early stages, DIC causes your blood to clot excessively. You may have a raised risk of bleeding with Eliquis if you already have a bleeding problem and if you take Eliquis in combination with other drugs that affect blood clotting. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Can poor sleep impact your weight loss goals? This could raise your risk of side effects, especially bleeding. If you drink alcohol, talk with your doctor about how much is safe to consume while taking Eliquis. Selected from data included with permission and copyrighted by First Databank, Inc. However, its possible you may gain weight due to the reason youre taking Eliquis. ELIQUIS is available in 2.5-mg and 5-mg tablets. Depending on appearance, some people may want to get rid of the keloids they have. In clinical trials, serious bleeding was rare with Eliquis. If you have questions about your risk of side effects from Eliquis, ask your doctor. Some of the potential drug-related causes include: SJS and TEN are serious reactions that can be life threatening. Do not run out of ELIQUIS. Do not run out of this medication. All rights reserved. If youre pregnant or breastfeeding, or planning for either, talk with your doctor about your treatment options. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Keep all medications away from children and pets. You may also consider discussing other risk factors with your doctor: Drug rashes may go away on their own once you stop taking the drug that caused your rash. Before you start taking this drug, tell your doctor about any bleeding disorder you have. For example, if you stop taking Eliquis earlier than your doctor recommends, this can raise your risk of blood clots. This document does not contain all possible drug interactions. If you are taking ELIQUIS for atrial fibrillation, stopping ELIQUIS may increase your risk of having a stroke. In fact, Eliquis has a boxed warning for the risk of blood clots if you stop Eliquis too early. Summary: After starting rivaroxaban for treatment of cancer-associated deep vein thrombosis (DVT) with pulmonary embolism (PE), a 69-year-old Caucasian woman arrived at an oncology clinic with a diffuse, exanthematous (morbilliform) rash on her neck . You may have nosebleeds during your treatment with Eliquis. With atrial fibrillation, part of the heart does not beat the way it should. The list below includes factors to consider. Before you start treatment with Eliquis, talk with your doctor about the possible side effects of this medication. The rest of the body was spared, and the remainder of examination was unremarkable. accessdata.fda.gov/drugsatfda_docs/label/2021/202155s034lbl.pdf, Common Medications for Atrial Fibrillation (AFib), Long-Term Blood Thinner Use: What You Need to Know, Ask the Expert: Common Questions About Alcohol and Blood Thinners, Blood Clots and Flying: What You Should Know, Disseminated Intravascular Coagulation (DIC): Symptoms, Causes, and Treatment, What to Know About Bleeding Diathesis: Causes, Symptoms, Treatment, risk of spinal blood clots from certain spinal procedures*, swelling under your skin, usually in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, an antihistamine you take by mouth, such as, a product you apply to your skin, such as hydrocortisone cream, what dose of the drug you were taking when you had the side effect, how soon you had the side effect after starting that dose, any other information you feel is important. 1 / 2 Look up another drug Find other drugs that treat. You might also find them inside your mouth or on your eyelids. Mild side effects that have been reported with Eliquis include: bruising. Here are some questions to help get you started: For tips on improving your heart health, sign up for Healthlines online newsletter. Having too much Eliquis in your body may increase your risk of side effects. What are the possible serious side effects of ELIQUIS? Be sure to talk with your doctor about your health history before you take Eliquis. When you take Eliquis, you may notice that you bruise easier or more often than usual. Bleeding problems. What should I discuss with my healthcare team before starting ELIQUIS? Don't soak the rash, but rinse it gently and pat it dry with a clean, dry towel. Learn. But its also possible to have serious side effects from this medication. Your doctor can recommend how long youll need to take the drug. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. In studies, the majority of people taking Eliquis were ages 65 years and older. However, drinking large amounts of alcohol may raise your risk of bleeding with Eliquis. Examples of mild side effects that have been reported with Eliquis include: In most cases, these side effects should be temporary. unexpected bleeding or bleeding that lasts a long time, such as unusual bleeding from the gums, nosebleeds that happen often, or menstrual or vaginal bleeding that is heavier than normal, bleeding that is severe or you cannot control, red, pink, or brown urine; red or black stools (looks like tar), coughing up or vomiting blood or vomit that looks like coffee grounds. Some drug rashes are severe and require emergency medical treatment. Bruises develop when capillaries burst after an impact, while blood clots occur when an injury damages blood vessels. Constipation and diarrhea have been reported with certain other blood thinners in the same class as Eliquis, such as Xarelto (rivaroxaban). Eliquis and Rashes - a phase IV clinical study of FDA data Summary: Rashes is found among people who take Eliquis, especially for people who are female, 60+ old, have been taking the drug for < 1 month. See below for more comprehensive information you should be aware of about bleeding and ELIQUIS. Heart failure: Could a low sodium diet sometimes do more harm than good? They include: Hemorrhage: Serious bleeding in the gastrointestinal tract Serious bleeding in the brain (hemorrhagic stroke) Serious bleeding within the eye Anemia Nausea generic drugs) are considered. (2020). Tell your doctor right away if you have tingling, numbness, or muscle weakness, especially in your legs and feet. If your doctor confirms youve had a serious allergic reaction to Eliquis, they may have you switch to a different treatment. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). We explain the connection between blood clots and flying, tips for prevention, and what you should know if you have a history of this condition. You and your doctor should decide if you will take ELIQUIS or breastfeed. Its a prescription drug used in adults to prevent or treat blood clots in certain situations. In some cases, they may recommend a different medication. Do not stop taking ELIQUIS without talking to the doctor who prescribed it to you. Lab and/or medical tests (such as hematocrit/hemoglobin, red blood cell count) may be done while you are taking this medication. A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. If you have minor bleeding that happens frequently or is bothersome, talk with your doctor. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Warfarin is an anticoagulant medicine (blood thinner). Tell your healthcare team about all the medicines you take, including any: During treatment, make sure you talk to your healthcare team before you begin to take any newmedication. As with many medications, higher dosages of Eliquis are more likely to cause side effects than lower dosages. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Additional symptoms are severe and can involve the internal organs, such as: Possible drugs that can cause DRESS include: DRESS is a very serious reaction that requires immediate medical attention. Learn about risks, signs to contact a doctor, and more. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Tip your head forward and breathe through your mouth while doing so. As such, the most common side effects of Eliquis include: Bleeding Bruising more easily than normal Anemia Other common side effects of Eliquis may include: Allergic reaction (skin rash, itching, flushing) Fatigue Nausea Headaches Dizziness 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Call your doctor for medical advice about side effects. *See eligibility requirements and terms of use. Read on to learn more about the different kinds of drug rashes, how theyre treated, and when you should seek medical care. Your doctor will also monitor you for symptoms of blood clots after you have a spinal procedure. In clinical trials, minor bleeding was the most common side effect reported with Eliquis. Ask your doctor what other medications may be better options for you. Petechiae are tiny purple, red, or brown spots on the skin. Should I avoid certain foods while taking Eliquis? More severe drug rashes, such as erythroderma, may cause permanent changes to skin pigmentation after treatment. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Side effects of 2.5-mg vs. 5-mg strengths, nonsteroidal anti-inflammatory drugs (NSAIDs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/202155s034lbl.pdf, Cardiovascular health: Insomnia linked to greater risk of heart attack. certain antibiotics, including tetracycline, SJS involves less than 10 percent of your body, a buildup of the drug that causes toxicity to the skin, a drug makes the skin more sensitive to sunlight, a viral infection and taking an antibiotic, a weakened immune system due to an underlying condition or other drug. The studies did not find an increased risk of Eliquis side effects in older people when compared with younger people. Talk to your healthcare team about the following: Tell your doctor if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed. Do not stop taking this medication without consulting your doctor. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. If you suspect you have a drug rash, talk with your doctor right away. Treat blood clots in the veins of the legs (deep vein thrombosis DVT) or lungs (pulmonary embolism PE), and reduce the risk of them occurring again. You and your doctor should decide if you will take ELIQUIS or breastfeed. Do not stop taking apixaban unless directed by your doctor. Weight gain wasnt reported in clinical trials of Eliquis. Wash the area with natural soap and warm water up to 3 times per day. Eliquis hasnt been reported to cause other long-term side effects (side effects that last for a long time). For patients taking ELIQUIS for atrialfibrillation: stopping ELIQUIS increases your risk of having a stroke. Drug rashes can appear as a variety of skin rashes, including pink to red bumps, hives, blisters, red patches, pus-filled bumps (pustules), or sensitivity to sunlight. This rash may develop suddenly or within hours, but it can take up to several weeks in some cases. ELIQUIS is a prescription medicine used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again. If you have a nosebleed, pinch the top of your nose tightly for 10 minutes to help stop the bleeding. Discuss the risks and benefits with your doctor. Eliquis has boxed warnings for the risk of blood clots if stopping Eliquis treatment early and risk of spinal blood clots from certain spinal procedures. For more information about Eliquis, including details about its uses, see this in-depth article. They can discuss your risk of side effects with you. See below for more important safety information about ELIQUIS. Tell your doctor right away if you notice symptoms such as back pain, leg numbness/tingling/weakness, loss of control of the bowels or bladder (incontinence). Examples include: If your doctor confirms youve had a mild allergic reaction to Eliquis, theyll decide if you should continue using it. Eliquis increases the risk of bleeding. Purpose: A case of a patient who developed a hypersensitivity reaction to rivaroxaban in the form of a diffuse, exanthematous rash is reported. In the US - Call your doctor for medical advice about side effects. You are a resident of the United States, Puerto Rico, or other select U.S. What are the more common side effects of Eliquis? You wont have withdrawal symptoms if you stop taking Eliquis, but you may have other side effects. This list doesnt include all possible mild side effects of the drug. TakingEliquis increases your risk of bleeding. This medication may cause stomach bleeding. If you need Adobe Reader, click the link below to download the free readerLink to Adobe Reader Download page. Another rare side effect of Eliquis is blood in the urine, which could be due to a kidney-related problem. Data obtained from you in connection with your registration for, and use of, this service may include your phone number and related carrier information. A drug rash or other reaction may occur for several reasons, such as: In some cases, drug rashes can be idiopathic, meaning theres no known direct cause. You may also experience a fever, with your skin feeling hot to the touch. Eliquis has a boxed warning for this side effect. Eliquis 5 mg tablet Color: pink Shape: oval Imprint: 894 5 This medicine is a pink, oval, film-coated, tablet imprinted with "894" and "5". Apixaban is used to prevent serious blood clots from forming due to a certain irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery. A head injury could cause bleeding inside your skull or in your brain while youre taking Eliquis. Females who are able to become pregnant: talk with your healthcare provider about pregnancy planning, and your risk of severe uterine bleeding if you are treated with blood thinner medicines, including ELIQUIS. In addition, certain medications are also commonly associated with skin manifestations such as petechiae. No, its not known to. This medicine is a pink, oval, film-coated, tablet imprinted with "894" and "5". Examples of drugs that can cause erythroderma, including: Certain underlying health conditions can also cause erythroderma, such as psoriasis and atopic dermatitis. Take a look at some of the most common types of drug rashes below: Exanthematous rashes are considered the most common type of drug rashes, accounting for about 90 percent of cases. The two companies were testing Eliquis, which includes apixaban, an orally-taken inhibitor which blocks a key blood-clotting protein, reducing the risk of thrombin generation and blood clots. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. Its not known if it may be safe to take Eliquis during pregnancy or while breastfeeding. Some people may experience mild to serious side effects during their Eliquis treatment. If you develop a side effect while taking Eliquis and want to tell the FDA about it, visit MedWatch. Eliquis will likely make the bleeding worse. Drugs that may cause . Card must be activated before use.